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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

N. Adachi

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Open access Aug 2026

Targeting Artemis sensitizes acute lymphoblastic leukemia cells to topoisomerase 2 poisons by disrupting DNA-PKcs-dependent repair

It is shown that the non-homologous end joining (NHEJ) enzyme Artemis is a key player in the process and a major target for treatment of human B-cell acute lymphoblastic leukemia (ALL), and genetic loss of Artemis ablates this synergy underscoring its critical role in this drug interaction.

Melissa L. Folkerts, C. Hom, Angie Nguyen et al. · 0 citations

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