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cfDNA fragmentomics of routine prenatal screening data identifies adverse pregnancy outcomes in immune-mediated disease (Stanley et al., this issue).
Supplemental Digital Content is Available in the Text. Among 263 adolescents with chronic musculoskeletal pain, the 3-item PEG scale accurately discriminated functional disability; a cut-off of 6 reliably identified high-impact chronic pain.
Self-reported pain remains the clinical standard for assessing musculoskeletal pain severity, but its subjectivity limits objective diagnosis, monitoring, and therapeutic development. We present LENS (Latent sEMG Neuromuscular Signature), which decodes exertion-evoked musculoskeletal pain intensity from surface electro...
Multisite functional Magnetic Resonance Imaging (fMRI) studies are rapidly becoming the norm to allow the acquisition of large samples required to perform advanced statistical techniques, e.g. machine learning. However, acquiring data at multiple sites includes methodological and technical challenges due to the differe...
Artificial intelligence (AI) may assist physicians by providing easy access to existing knowledge and discerning data patterns, perhaps previously unrecognized, however, whether AI can replace human decision-makers altogether remains an open question.
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