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N. Amer

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Open access Oct 2026

Sex-specific impact of chronic kidney disease on mortality and dialysis in heart failure with metabolic syndrome

Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic disorder defined by the overlapping burden of heart failure (HF), chronic kidney disease (CKD), diabetes, and obesity. Although sex differences in cardiovascular disease are increasingly recognized, sex-specific patterns of mortality and renal progressi...

D. Hochstein, R. Loutati, V. Copeland et al. · 0 citations
Open access Oct 2026

Chronic kidney disease in metabolic syndrome and heart failure: elevated risk, underutilized therapies, and missed opportunities for improved outcomes

In patients with late-stage metabolic syndrome, CKD identifies a high-risk subgroup with a graded increase in mortality and dialysis risk compared with eGFR ≥60, and the heightened dialysis risk remained pronounced after accounting for competing death.

D. Hochstein, R. Loutati, V. Copeland et al. · 0 citations

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