Chalcones as versatile scaffolds in drug design: synthesis, structure–activity relationship (sar), and anticancer potential
Chalcones, 1,3-diaryl-2-propen-1-ones, represent a structurally simple yet highly versatile class of α, β-unsaturated carbonyl compounds that have gained considerable attention in anticancer drug discovery. The persistent emergence of drug resistance, off target toxicity, and tumor heterogeneity drives the search for t...