Parkinson’s disease is increasingly recognized as a heterogeneous syndrome characterized by diverse pathological processes and clinical manifestations. Here, we propose a multidimensional framework to assess this heterogeneity, with each dimension potentially captured using advanced magnetic resonance imaging technique...
M. Pokotylo, N. Bruggemann, Jannik Prasuhn· npj Parkinson's Disease· 0 citations
In this study, we designed a gene panel based on Nanopore long-read sequencing using adaptive sampling, targeting n = 564 genes associated with Parkinson’s disease (PD) and repeat expansion disorders. We investigated its diagnostic utility in n = 18 patients with (1) pathogenic variants in LRRK2, PRKN, SNCA, and RAB32...
A. Fienemann, J. C. Prietzsche, Joshua Laβ et al.· npj Parkinson's Disease· 0 citations
BACKGROUND
Long-term memory for novel information can be supported by presenting it within a known semantic context. This so-called congruency effect has long been described as an example of schema-dependent learning, but the underlying neural mechanisms still remain unclear. Therefore, we tested the hypothesis that do...
Mushfa Yousuf, N. Kloosterman, Jannik Prasuhn et al.· Journal of Psychopharmacolog...· 0 citations
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