Author

N. Chang

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Review Open access Aug 2026

Molecular and Cellular Mechanisms Linking Mood Disorders, HPA Axis Dysregulation, and Neurocognitive Inflammation to Perioperative Neurocognitive Disorders

Patients with preexisting mood disorders may enter surgery in a biologically sensitized neuroimmune state, lowering the threshold for exaggerated neuroinflammatory responses and postoperative cognitive dysfunction, according to a review of convergent pathophysiologic pathways.

Alyson Sato, N. Chang, N. Knezevic et al. · Biomolecules · 0 citations

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