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N. Dits

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Open access Aug 2026

Surface Proteomics of Cancer-Derived Extracellular Vesicles Reveals Universal Heat Shock Proteins and Cancer Signatures

Extracellular vesicles (EVs) secreted by cancer cells are a valuable source of noninvasive biomarkers, as they are released into biofluids and reflect the molecular makeup of their cells of origin. To enable direct capture and detection of cancer-derived EVs, detailed knowledge of their surface proteome is essential. H...

L. Erozenci, Fenna Feenstra, S. Piersma et al. · 0 citations
Open access Jul 2026

Small-scale bioreactor cultivation of HEK293-based suspension cells increases extracellular vesicle yield

It is demonstrated that Expi293F-derived EV yield can be increased by culturing cells in a scalable bioreactor system, paving the way towards the production of therapeutic-based EVs in a scalable and reproducible manner suitable for future (pre-)clinical applications.

W. Woud, E. Dilla, N. Dits et al. · 0 citations

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