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Author

N. Gadewal

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Open access Aug 2026

Mitocurcumin mediated redox disruption and metabolic rewiring induces tumor regression in Drosophila intestinal stem cell tumors

Mitochondria-targeted modulation of redox homeostasis has emerged as a promising strategy for controlling pathological cell proliferation. Here, we investigate the effects of Mitocurcumin in a Yorkie-driven intestinal stem cell tumor model in Drosophila. Using an integrative, genetically tractable approach combining in...

Somesh Diwate, Ujjayita Chowdhury, N. Gadewal et al. · 0 citations
Aug 2026

Virtual Screening, Molecular Dynamics, and Density Functional Theory Identify Piperolein A as a Putative Dual PPARα/γ Modulator Relevant to Radiation‐Induced Cognitive Decline

Radiation‐induced cognitive decline (RICD) is a debilitating late effect of cranial radiotherapy characterized by persistent oxidative stress, neuroinflammation, and impaired hippocampal neurogenesis. Given the established roles of peroxisome proliferator‐activated receptors α and γ (PPARα/γ) in regulating inflammato...

Jemema Agnes Tripena Raj, Isha Shinde, Abhishek Chatterjee et al. · 0 citations

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