Author

N. Gaïa

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Open access Aug 2026

Training a phage to expand its host range: directed evolution against Staphylococcus aureus from diabetic foot infections

ABSTRACT Diabetic foot infections (DFIs) are a major complication of diabetes frequently involving multidrug-resistant Staphylococcus aureus. Their persistence and therapeutic complexity underscore the urgent need for alternatives to conventional antibiotics. Phage therapy offers a promising solution, though its clinic...

Lucile Plumet, Chloé Magnan, M. Morsli et al. · Antimicrobial Agents and Che... · 0 citations

Open access Jul 2026

A secreted AIP-Like peptide from Helcococcus kunzii inhibits the Agr quorum sensing system of Staphylococcus aureus

It is demonstrated that Adh2 suppresses Agr signaling and virulence gene expression while promoting a persistent phenotype, and emerges as a promising candidate for therapeutic modulation of bacterial behavior, particularly in the context of chronic wound infections.

Riham Daher, P. François, R. Vincentelli et al. · Virulence · 0 citations