Open access
Sep 2026
Differential Regulation of Soluble and Membrane 4-1BB and OX-40 Within the Peripheral Compartment of Cervical Cancer
Background: Members of the tumor necrosis factor receptor superfamily (TNFRSF), including 4-1BB (CD137) and OX-40 (CD134), play central roles in regulating cytotoxic lymphocyte activation and anti-tumor immunity. In addition to their membrane-bound forms, soluble receptor isoforms may modulate signaling by influencing...
J. Rojas-Diaz, Fernando Galvan-Ledezma, Ksenia Klimov-Kravtchenko et al.
· Receptors · 0 citations