Author

N. Geijsen

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Open access Aug 2026

CRISPR activation reveals SOX5/6/9 as key transcriptional regulators directing iPSC-derived cells toward a notochordal lineage

This study demonstrates the integration of CRISPRa with single-cell technologies as a powerful platform for investigating and enriching iPSC-derived NCs, supporting future regenerative strategies across various fields.

Xiao-Le Tong, Marieke Visscher, F. Riemers et al. · Stem Cell Reports · 0 citations