Stem Cell Repor ts
Self-cloning CRISPR/Cas9 (scCRISPR), a technology that allows for CRISPR/Cas9-mediated genomic mutation and site-spe-cific knockin transgene creation within several hours by circumventing the need to clone a site-specific single-guide RNA (sgRNA) or knockin homology construct for each target locus, substantially lowers the bar on mouse and human transgenesis.
Mandana Arbab, Sharanya Srinivasan, Tatsunori Hashimoto et al.
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