Author

N. H. Mohd Nor

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Review Aug 2026

Structural and Ultrastructural Neuropathological Changes in Alzheimer's Disease: Biomarkers, Current Insights and Emerging Perspectives.

Alzheimer's Disease (AD) involves progressive brain changes at both the structural and ultrastructural levels, which begin long before patients present with clinical symptoms. These changes relate to the complex processes of amyloid-β deposition, tau accumulation, synaptic damage, glial activation, impaired vascular fu...

S. Sura, E. O. Okwuofu, Sowmya Ramakrishnappa et al. · Current Alzheimer Research · 0 citations

Review Aug 2026

Tau dysfunction in alzheimer’s disease: molecular and cellular mechanisms, genetic modulation, and therapeutic perspectives

Findings support a model in which tau dysfunction results from the convergence of molecular aberrations and genetic susceptibility within a pathological network involving amyloid-β, neuroinflammation, and synaptic failure.

S. Sura, S. Jagadeesan, M. A. M. Moklas et al. · Molecular Biology Reports · 0 citations