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N. Hansell

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Open access Aug 2026

Mitigating Bias in Health-Related Quality of Life (HRQoL) Estimation Due to Missing Data: A Simulation-Based Study Evaluating Imputation Methods

A preliminary policy is developed that could be used for HTA submissions, if the missingness pattern is not known and missingness ≤5%, that suggests MICE-based techniques are used as the base case for missingness >5%, and delta-PMM used as a sensitivity analysis when data are not MCAR.

Joe W. E. Moss, N. Hansell, Erin Barker et al. · 0 citations

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