Thermosensitive Alginate/Carrageenan–Stearic Acid Dissolving Microneedles Incorporating Liposome-Coated Hollow Mesoporous Silica Nanoparticles for Controlled Caffeine Delivery
Caffeine is a promising active for topical pharmaceutical and cosmetic applications; however, its hydrophilic nature can limit passive transport across the stratum corneum and reduce local retention. Although nanoparticle-loaded dissolving microneedles have been explored, few systems combine a hollow porous carrier, a...