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Open access Sep 2026

Genotoxic and metabolic stress drive divergent senescence programs in human microglia

Investigating the impact of chronic genotoxic and metabolic stress on senescence-associated phenotypes in the human microglia cell line HMC3 demonstrated that chronic genotoxic and metabolic stress drive distinct yet overlapping senescence programs characterised by morphological changes, mitochondrial remodelling and p...

N. Jose, S. Janssens, Eunchai Kang et al. · 0 citations

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