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Author

N. Kootstra

2 papers indexed here

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Open access Jul 2026

Siglec-1-targeted nanobodies restrict HIV-1 transmission and infection of dendritic cells

ABSTRACT Human immunodeficiency virus 1 (HIV-1) remains a global health burden affecting over 39 million people worldwide, with approximately one million new infections occurring each year. Sexual transmission remains the predominant route of HIV-1 acquisition, during which the virus crosses mucosal barriers and intera...

S. Man, A. Affandi, H. Brink et al. · 0 citations
Open access Aug 2026

Capsid-Targeting Biologic Achieves Broad HIV-1 Neutralization with a High Barrier to Resistance

The results demonstrate the broad neutralization potential of anti-capsid biologics with a high barrier to resistance, making capsid-targeting inhibitors important for novel antiretroviral drug strategies worldwide.

F. M. Stel, E. Zijlstra-Willems, A. van Nuenen et al. · 0 citations

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