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Review Open access Sep 2026

Immunotherapy for Newly Diagnosed Glioblastoma: Current Evidence and Future Perspectives

Background: Glioblastoma (GBM) represents the most aggressive and lethal primary malignancy of the central nervous system in adults. Although clinical trials evaluating immunotherapy strategies have increased substantially in recent years, the available evidence remains highly fragmented. This scoping review aimed to s...

R. Arend, B. Peroni, N. Lima et al. · 0 citations
Review Sep 2026

Vagus nerve stimulation in pediatric patients with Lennox-Gastaut syndrome: a systematic review.

BACKGROUND This study evaluates the efficacy and safety of Vagus Nerve Stimulation (VNS) in the treatment of refractory Lennox-Gastaut Syndrome (LGS) in pediatric patients. METHODS A systematic literature review was conducted based on observational studies and case series analyses, followed by assessment of risk of b...

João Cândido Spezia de Souza, Marina Ilha Zimmermann, N. Lima et al. · 0 citations

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