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N. Lomri

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Open access Sep 2026

Impact of ATP8B1 Mutation and Maturation on CFTR Functionality and Gene Expression

A physical association between ATP8B1 and CFTR is revealed, supporting a chaperone role for ATP8B1 in CFTR trafficking and membrane insertion and providing new insights into the molecular link between PFIC1 and cystic fibrosis-associated liver disease.

J. Sergent, C. Hulen, N. Lomri · 0 citations

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