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Open access Aug 2026

Detection of intratumoral hypoxia in primary breast cancer using photoacoustic imaging

Background Tumor hypoxia and abnormal vasculature are closely associated with aggressiveness in solid tumors. Therefore, noninvasive assessment of these features in primary breast cancer is needed. Photoacoustic (PA) imaging is an emerging modality that enables real-time visualization of vascular architecture and hemog...

H. Shimizu, M. Kawashima, M. Kataoka et al. · 0 citations
Open access Aug 2026

Multicenter development and validation of a serum microRNA–based diagnostic model for breast cancer and its association with tumor burden and biological aggressiveness: an observational case-control study

Although mammography remains the cornerstone of breast cancer screening, its diagnostic performance is influenced by factors such as breast density and tumor characteristics. Blood-based biomarkers may therefore provide complementary biological information to imaging-based detection strategies. While circulating...

A. Yamaguchi, Kana Kawanishi, Kei Ishii et al. · 0 citations

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