Review
Open access
Sep 2026
uPAR-directed immunotherapies in solid tumors: current advances and future perspectives
In cancer, elevated expression of the urokinase-type plasminogen activator receptor (uPAR) is a well-established adverse prognostic factor associated with enhanced tumor invasion, metastatic dissemination, cellular proliferation, and resistance to conventional therapies. Genetic ablation or silencing of uPAR has been...
Filomena Napolitano, N. Montuori
· Frontiers in Pharmacology · 0 citations