Author

N. Naffakh

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Open access Jul 2026

Affinity-enhanced peptides delivered by mRNA–LNPs inhibit influenza A virus replication by disrupting the PA-PB1 interaction

This work establishes intracellularly expressed peptide inhibitors as a viable antiviral strategy and provides a generalizable framework for targeting essential protein-protein interactions of influenza and other RNA viruses.

Alberto Florez Prada, Chloé Sturmach, Nabila Laroui et al. · bioRxiv · 0 citations

Open access Aug 2026

Nucleocapsid-like cryo-EM structure of influenza B virus

Overall, the results suggest that vRNPs from influenza virus type A, B and D share the same right-handed antiparallel helical conformation and that the B/NP N-terminal tail does not participate to the helical architecture stabilization once the vRNPs are assembled.

Marie Thirion, A. J. Stelfox, Florian Chenavier et al. · PLoS Pathogens · 0 citations