Abstract Background Chronic stress profoundly affects brain function and constitutes a major risk factor for both psychiatric and systemic pathologies. Understanding its impact necessitates an integrated approach linking behavioural, molecular, and neural mechanisms. While biological variables such as sex and circadian...
M. Giovenzana, J. Mingardi, P. Misztak et al.· International Journal of Neu...· 0 citations
Preliminary findings suggest that the in vitro stress protocol induces structural and synaptic alterations, and that ketamine rapidly affects expression of several proteins involved in synaptic plasticity.
N. Nicosia, J. Mingardi, G. Terribile et al.· International Journal of Neu...· 0 citations
Results show that synapsin deletion is associated with a distinct profile of social and repetitive behavioral abnormalities, accompanied by a region-selective alteration in IL-mPFC firing activity, which indicates a marked deficit in sociability and social recognition in TKO mice.
Noemi Nicosia, Elena Monzani, Maria Regoni et al.· Progress in Neuro-psychophar...· 0 citations
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