N. O. Pérez

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli : Tuning inclusion body architecture and protein yield via dissolved oxygen control

Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural character...