Author

N. Parajuli

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Open access Oct 2026

Molecular Docking and Molecular Dynamics Simulation Studies of Human Pancreatic α-Amylase with Phytochemicals from Corydalis chaerophylla D.C.

Diabetes mellitus, a chronic metabolic disorder resulting from hyperglycemia, is responsible for millions of deaths worldwide. The hyperglycemic index can be reduced through the inhibition of human pancreatic α-amylase (HPAA), an enzyme associated with the cleavage of α-(1,4)-D-glycosidic bonds for the conversion of st...

Binita Maharjan, N. Parajuli, T. Shrestha et al. · Amrit Research Journal · 0 citations

Open access Oct 2026

Multi-Omic Analyses Reveal VPS72 Associations with Chromatin Remodeling, Proliferation, and Stress-Response Programs Across Human Cancers

Malignant cells hijack epigenetic processes to sustain proliferation and to tolerate stressors that would otherwise limit cell growth, yet the chromatin remodeling activities that establish and maintain these programs are poorly defined. H2A.Z is a histone variant deposited into nucleosomes by the SRCAP and TIP60 chrom...

X. Solone, Md-Selim Reza, Paul A. Renauer et al. · International Journal of Mol... · 0 citations

Open access Oct 2026

Exploring the Bioactive Potential of Ficus benghalensis L. Leaves: Phytochemical Profiling and In Vitro Biological Evaluation

Ficus benghalensis L. (Bar) is a medicinally valued plant containing a diverse range of phytochemical constituents. The present study evaluated the phytochemical profile and biological activities of hexane, chloroform, and methanol leaf extracts obtained by ultrasound-assisted extraction. Phytochemical screening reveal...

Sujita Mali, Kamana Shahi Thakuri, N. Parajuli et al. · Amrit Research Journal · 0 citations