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N. Pfarr

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Open access Sep 2026

Analytical and Biological Factors Associated with Oncogenic Variant Yield in Tumor-Agnostic Plasma ctDNA Profiling

Background/Objectives: Tumor-agnostic plasma ctDNA profiling is used when tumor tissue is unavailable, insufficient, or unrepresentative. We investigated analytical and biological factors associated with oncogenic variant yield. Methods: In the prospective EXMASTER study, plasma cfDNA was analyzed using a 265-gene targ...

Stephen George, L. Ranganathan, Yi-Zhen Xiang et al. · 0 citations

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