Open access
Oct 2026
The landscape of polygenic score prediction accuracy and transportability across the phenome in ancestrally diverse populations
Polygenic scores (PGS) are increasingly common in human genetics research, yet their performance and portability vary substantially across traits and populations. We systematically evaluate prediction accuracy and cross-ancestry portability for 3,994 published PGSs across the phenome in the ancestrally diverse CCPM bio...
M. Lin, C. Arehart, S. N. K. Walker et al.
· medRxiv · 0 citations