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Review Open access Aug 2026

Farnesol as a Multifunctional Regulator of Fungal Biology: Mechanisms and Significance

Farnesol is a small isoprenoid metabolite that has emerged as a key regulator of fungal biology beyond its original identification as a quorum-sensing molecule in Candida albicans. This review examines farnesol across pathogenic and non-pathogenic fungi, emphasizing its roles in morphogenesis, biofilm development, stre...

Shaurya Prakash, N. Rai, Sandhya Shukla et al. · 0 citations
Open access Sep 2026

Excessive EFHD1-dependent ER-mitochondrial contacts drive a maladaptive antiviral response in metabolic liver disease.

Metabolic-associated steatohepatitis (MASH) involves hepatocyte damage that cannot be explained solely by lipid accumulation. Here, to discover injury-specific pathways, we focused on a gene of uncertain function, EF-Hand Domain Family Member D1 (EFHD1), identified in human genome-wide association studies of liver inju...

D. Eberhardt, Emma C. Rekate, Yasmin B. Masini et al. · 0 citations

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