N. Rezaei-Ghaleh

Microtubule Binding of a Tau Peptide Monitored through Fluorine NMR Probes

Binding of tau protein to microtubule (MT) supports the stability and cellular functions of MT. Aberrations in tau-MT binding are linked to several neurodegenerative diseases. Little is known about how regions outside the four canonical MT-binding repeat regions of tau protein (R1–R4) are involved in MT binding. Here...