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Open access Sep 2026

Small extracellular vesicles from the plasma of head and neck cancer patients induce dysfunctional T cell phenotypes.

BACKGROUND Head and neck cancer (HNC) is highly immunosuppressive. Despite advances with immune checkpoint (IC) inhibitors, many HNC patients fail to respond. Tumour-derived small extracellular vesicles (sEVs) may contribute to immune evasion and therapy resistance, possibly by altering T-cell phenotypes. METHOD Plas...

Luisa Tengler, Edwin K. Jackson, K. Bieback et al. · 0 citations

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