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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Nidhi Sahni

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3 papers indexed here

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Open access Sep 2026

Functional characterization of viral transcriptional regulators reveals extensive rewiring of host pathways

Viral transcriptional regulators (vTRs) reprogram host gene regulatory networks to promote replication, persistence, and immune evasion. Despite the identification of hundreds of vTRs in human viruses, how they rewire host pathways remains unclear. Here, we systematically profiled 95 vTRs from diverse human viruses acr...

Jaice T. Rottenberg, Xing Liu, M. Y. ElSadec et al. · 0 citations
Jul 2026

Cell cycle-coupled transcriptional network regulates human B cell fate bifurcation 2257411

A generalizable framework for assembling and testing GRNs in the context of immune cell fate decisions is established, and previously unreported feedback loops that link cell division to fate specification are revealed.

Nicholas A. Pease, Jing-Yu Fan, S. Keshari et al. · 0 citations
Open access Aug 2026

Suppression of EGFR signaling and drug-induced potentiation are widespread features of oncogenic RTK fusions.

It is uncovered that a large number of RTK fusions simultaneously act as both activators and suppressors of signaling, the mechanisms of which could be exploited for biomimetic therapies that enhance cell killing and suppress drug tolerance.

Yu-Zhi Gao, D. Gonzalez-Martinez, Sofia Wissert et al. · 0 citations

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