Biophysics and Physicobiology
Tohru Minamino, Motoshi Sakai, M. Kinoshita et al.
· 0 citations
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Open access
Sep 2026
Structural basis for substrate specificity switching revealed by the FlhA(A489E) suppressor mutation
The flagellar type III secretion system (fT3SS) switches its substrate specificity from hook-type to filament-type upon completion of hook assembly. This process is regulated by the coordinated actions of FliK, FlhB, and FlhA, but the structural mechanism underlying substrate specificity switching remains unclear. Here...
Motoshi Sakai, M. Kinoshita, N. Takekawa et al.
· Biophysics and Physicobiolog... · 0 citations
Open access
Jul 2026
Detection of Ring Structure and Its Flexibility in Periplasmic Region of FliL, Bacterial Flagellar Stator-Associate Protein, in Marine Vibrio.
Analysis of oligomeric organization and structural plasticity of the periplasmic domain of polar-flagellum FliL from Vibrio alginolyticus and compared with detergent-solubilized full-length pofFliL suggests that such plasticity enables FliL to act as an adaptable scaffold for stator engagement and mechanosensitive remo...
Tatsuro Nishikino, N. Takekawa, Raymond N. Burton-Smith et al.
· Molecular Microbiology · 0 citations