The Development and Application of a ChemBead-Enabled On-DNA HTE Platform for Challenging C–N Couplings
In this work, we present the creation and implementation of a ChemBead-enabled, on-DNA high-throughput experimentation (HTE) platform to identify more general and mild reaction conditions for challenging C–N couplings. The platform was developed by adapting our small-molecule system to address the inherent challenges...