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Author

N. Ujagar

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Open access Aug 2026

Endocrine-Adapted Pituitary Macrophages Regulate Gonadotropin Secretion through CXCL5-CXCR2-MAPK Signaling

Chronic inflammation disrupts hormonal balance in the Hypothalamic-Pituitary-Gonadal (HPG) axis, contributing to reproductive disorders. While immune cells in the hypothalamus and ovaries have been extensively studied, their impact on the pituitary remains largely unexplored. Our research identifies pituitary macrophag...

Z. Del Mundo, J. Ha, Lily Zhou et al. · 0 citations
Open access Aug 2026

Systems genetics approaches model the heritable architecture of polyendocrine metabolic ovarian syndrome.

It is shown that increased ovarian area contributes to both PMOS susceptibility and ovarian cancer progression, while specific ovary-heart signaling circuits modulate cardiac function with aging, and SF3B1-mediated splicing is uncovered as a link between ovary function and systemic metabolism.

Christy M. Nguyen, L. Velez, Youngseo Cheon et al. · 0 citations

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