Author

N. Vokes

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Review Jul 2026

The Quest to Cure Metastatic Non-Small Cell Lung Cancer With Immunotherapy.

The introduction of immune checkpoint inhibitors targeting the programmed death-1 (PD-1) axis represented a major therapeutic advance, enabling long-term survival, and even cure, in a subset of patients, an outcome previously considered unattainable in metastatic disease. However, most patients do not yet derive sustai...

D. Boiarsky, N. Vokes · Cancer Journal · 0 citations

Open access Jul 2026

The genomic landscape and treatment outcomes associated with CDKN2A/MTAP loss in patients with non-small cell lung cancer.

INTRODUCTION Homozygous deletion of 9p21, containing CDKN2A/B and MTAP (CMdel), underlies emerging therapeutic strategies including PRMT5/MAT2A inhibition. The clinicogenomic context and treatment outcomes of CMdel in NSCLC remain incompletely defined. METHODS We analyzed Tempus Lens records with paired DNA/RNA seque...

N. Vokes, J. Symons, Brooke Rhead et al. · Clinical Cancer Research · 0 citations