Microbial halogenated natural products (hNPs) hold ecological, agricultural, and biomedical relevance. The hNP-producing potential of an organism can be assessed by the precise prediction of halogenating enzymes, yet detailed annotations of halogenases are often missing from genomic and metagenomic data. We created a m...
Judit Szenei, Ashleigh Burke, Anne Liong et al.· ACS Omega· 0 citations
Genomic and metagenomic studies have revealed that microbes have the capacity to produce an enormous diversity of secondary metabolites. These compounds play important roles in microbial interactions and are also a major source of medicines and other useful natural products, yet only a small fraction of this biosynthet...
Caner Bağcı, Alec Talamas-Tanner, N. Ziemert· bioRxiv· 0 citations
antiSMASH is widely used for biosynthetic gene cluster (BGC) detection and annotation, but its standard workflow is poorly suited to large metagenomic assemblies, where massive contig counts create severe runtime bottlenecks and complicate downstream result exploration. We present metaSMASH, a re-engineered fork of ant...
Caner Bağcı, Kai Blin, N. Ziemert· bioRxiv· 1 citation· ⚡1
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.