Na Guo

Development and validation of a LASSO-selected machine learning prediction pipeline for predicting coronary artery calcification in a health check-up population

Background Coronary artery calcification (CAC) screening in young, asymptomatic populations is clinically valuable but constrained by CT radiation and cost. We developed and calibrated a parsimonious, interpretable machine learning model using routine health check-up variables to identify CAC-positive individuals suita...