Author

Nader I. Al-Dewik

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Open access Aug 2026

Gene expression profiling of maternal plasma, urine, and blood reveals molecular signatures of placenta accreta and low-lying placenta

Placenta accreta spectrum (PAS) and low-lying placenta (LLP) are major obstetric disorders associated with life-threatening hemorrhage and adverse maternal outcomes. Despite advances in imaging, accurate prenatal differentiation between these conditions remains challenging. Liquid biopsy approaches using maternal bio...

Thomas Farrell, BalaSubramani Gattu Linga, Faisal E. Ibrahim et al. · Scientific Reports · 0 citations

Open access Aug 2026

Machine Learning Triage of LDLR Variants of Uncertain Significance Using Predictor Concordance and ACMG-Aligned Evidence Mapping

Background: Variants of uncertain significance (VUS) in the LDLR gene remain a major barrier to the molecular diagnosis of familial hypercholesterolemia. Although computational approaches offer scalable prioritization, their clinical utility is limited by predictor discordance, incomplete annotations, and inflated perf...

BalaSubramani Gattu Linga, Faisal E. Ibrahim, Nader I. Al-Dewik · Genes · 0 citations