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Nadja K. Hoffmann

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Review Open access Sep 2026

Metal-catalyzed phosphorylation by phosphite and energy at origins.

How did phosphate become the universal energetic currency of life? Traditional approaches to phosphorylation in early evolution studies entail non-physiological conditions. Phosphite, HPO32-, which is oxidized enzymatically by many microbes and which naturally occurs in serpentinizing hydrothermal vents, readily phosph...

Nadja K. Hoffmann, M. L. Schlikker, W. F. Martin · 0 citations

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