2026
Identification of key genes and pathways involved in trastuzumab resistance in HER2-positive gastric cancer through integrative bioinformatics analysis
Objective(s): Trastuzumab resistance limits therapeutic efficacy in HER2-positive gastric cancer, and its systems-level regulatory architecture remains poorly characterized. This study aimed to identify key regulatory modules, biomarkers, and candidate therapeutic targets associated with trastuzumab resistance. Materia...
Feng Wang, N. Mottaghi-Dastjerdi, Fatma Altameemi et al.
· Iranian Journal of Basic Med... · 0 citations