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Nalberth B. Farias

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Open access 2026

Discovery of Natural Alkaloid Inhibitors of NLRP3 Inflammasome: A Computational Approach Leveraging Brazilian Biodiversity

The NLRP3 inflammasome (NLR family pyrin domain-containing 3) plays a central role in the pathogenesis of several chronic inflammatory diseases, including rheumatoid arthritis, type 2 diabetes mellitus, and Alzheimer disease. However, currently available inhibitors, such as MCC950, present important limitations related...

Nalberth B. Farias, J. D. da Rocha, R. D. de Barros et al. · 0 citations

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