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Author

Namita Kumar

1 paper indexed here

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Open access Aug 2026

M5542, a bifunctional fusion protein targeting CD80, CD86, and OX40L that modulates excessive T-cell activity: a preclinical proof-of-concept study

The bifunctional M5542 blocked CD28 and OX40-mediated T-cell inflammation with greater immunomodulatory activity than monofunctional agents and in some assays comparable to or better than the combination of the monofunctional agents.

Michelle Downing, Allison F. Christiaansen, Ling Zhang et al. · 0 citations

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