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Author

Nannan Wang

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Open access Oct 2026

CD73-targeted CAR-NK cell therapy displays potent antitumor activity and translational potential in relapsed/refractory lung adenocarcinoma

Preclinical evidence is provided that CD73-CAR-NK cells exhibit potent antitumor efficacy for R/R LUAD through their dual functions of eliminating CD73-high tumor cells and resisting adenosine-mediated immunosuppressive signaling, supporting their therapeutic potential.

Qian-Qian Liu, Qi-Fei Dong, Yi-Mei Chen et al. · 0 citations
Review Open access Aug 2026

The Role of Alternative Splicing in Lung Cancer: Mechanisms, Regulators, and Therapeutic Implications

This review summarizes the multifaceted roles of AS in lung cancer biology, highlighting its contributions to tumor evolution, metastatic dissemination, and treatment resistance and its potential implications for biomarker discovery and precision therapeutic strategies targeting splicing dysregulation.

Lingrui Shang, Nannan Wang, Qianqian Liu et al. · 0 citations

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