Female reproductive health depends on precisely coordinated metabolic, hormonal, immune, and epigenetic networks. Lactylation is a lactate-derived lysine post-translational modification that provides a direct mechanism by which glycolytic metabolism influences chromatin activity and protein function. Lactylation exerts...
Xiao-Yang Shen, Yan Chen, Hong-Xia Deng et al.· Frontiers in Pharmacology· 1 citation
Obesity is a chronic metabolic disorder characterized by excessive adipose tissue accumulation and associated with systemic oxidative stress, mitochondrial dysfunction, and chronic low-grade inflammation. Adipose tissue dysfunction promotes the overproduction of reactive oxygen species through multiple mechanisms, incl...
Rong-Yu Wang, Ying-Yu Luo, Li-Ying Liu et al.· Antioxidants· 0 citations
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