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Jul 2026

In Silico Design of High-Affinity Antibody VRC34.01 for HIV-1 Fusion Peptide Recognition.

Detailed molecular dynamics simulations combined with free energy perturbation calculations were used to systematically investigate the effects of point mutations on both the fusion peptide and the antibody, providing a quantitative and structural framework for understanding fusion peptide recognition.

Mei Feng, Nan Wang, Yi Song et al. · 0 citations

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