Nancy W. Nashat

Spectrophotometric determination of levofloxacin using bromophenol blue: insight into the structure of the formed supramolecular complex

Levofloxacin was determined using a spectrophotometric method based on the formation of a hydrogen-bonded supramolecular complex with bromophenol blue. The method was linear over 1–20 µg mL−1, with a limit of detection of 0.39 µg mL−1. It was successfully applied to commercial tablet formulations (250, 500, and 750 mg)...