Open access
Aug 2026
Zfp217 Regulates Hepatic de Novo Lipogenesis via METTL3-Mediated N6-Methyladenosine Modification of SREBF1.
Zinc finger protein 217 (Zfp217) mediates adipogenesis via an N6-methyladenosine (m6A)-dependent mechanism; however, its role in hepatic lipid metabolism is unexplored. Nonalcoholic fatty liver disease (NAFLD), characterized by hepatic triglyceride (TG) accumulation resulting from disrupted lipid homeostasis, lacks wel...
Shuangshuang Li, Qianhui Zeng, Ya-Dan Liu et al.
· The FASEB Journal · 0 citations