Oral squamous cell carcinoma (OSCC) develops through multiple pathogenic and environmental factors. Increasing evidence suggests that the oral microbiota, particularly intratumoral bacteria, is also associated with OSCC progression; however, the relationship between individual bacterial subspecies and the tumor immune...
Cancer-associated fibroblasts (CAFs) are key regulators of tumor progression, immune modulation, and therapeutic resistance within the tumor microenvironment. Advances in single-cell and spatial profiling have revealed substantial heterogeneity among CAF populations, challenging the traditional view of CAFs as a unifor...
Y. Fukui, Hiroaki Kasashima, Nobuhiro Naito et al.· JMA Journal· 0 citations
An energy landscape analysis-based framework is applied to characterize transitions in gut microbiota along a clinical gradient of liver disease severity, as measured by the FibroScan-AST (FAST) score, indicating that liver disease progression is associated with structured transitions in microbial community organizatio...
Kenta Suzuki, Tomonori Kamiya, H. Fujii et al.· bioRxiv· 1 citation
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