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Author

Naotoshi Iwahara

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Oct 2026

SIRT1 Regulates Late Stage of Autophagy and Mitophagy via Autophagosome–Lysosome Fusion in Cardiomyocytes

Sirtuin‐1 (SIRT1) is an NAD+‐dependent deacetylase implicated in autophagosome formation; however, whether SIRT1 also regulates autophagosome clearance during late‐stage autophagy remains unclear. Here, we investigated the role of SIRT1 in autophagosome clearance during autophagy and mitophagy in cardiomyocytes. Mitoch...

Atsushi Kuno, Yukika Saga, R. Hosoda et al. · 0 citations

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