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Author

Natalie Kazmierowicz

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Open access Aug 2026

Myeloid-derived MIF is a central regulator of MDSC-driven T-cell dysfunction in head and neck squamous cell carcinoma

These findings identify myeloid-derived MIF as a central regulator of the MDSC–Treg–CD8⁺ axis in HNSCC and support myeloid-targeted MIF inhibition as a strategy to reprogram the TME and enhance responses to immune checkpoint blockade.

Suvekshya Shrestha, F. Lamenza, Natalie Kazmierowicz et al. · 0 citations

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